EMPIRICA Therapeutics

Developing a pipeline of innovative and transformative immunotherapies for cancers with substantial unmet need

ABOUT US

The engine behind Empirica is a powerful functional genomics platform combined with unique patient-based models of brain cancer and recurrence, which are enabling the discovery of new therapeutics options that have emerged from the patient’s actual tumour biology. The company is focused on the development of adoptive immunotherapies against the most aggressive and treatment-resistant forms of cancers, including glioblastoma (GBM) and brain metastasis (BM). 


Empirica Therapeutics was founded in July 2018 by Dr. Sheila Singh, a pediatric neurosurgeon, and Dr. Jason Moffat, an expert in functional genomics and gene-editing platforms.

TECHNOLOGY

The first product in Empirica’s preclinical pipeline is eCAR-133. eCAR-133 is based on genetically engineered T cells with chimeric antigen receptors that specifically bind to a CD133 antigen to recognize and kill the cancer cells. 


The Empirica team has validated CD133 as an essential marker of therapy-resistant GBMs and developed eCAR-133 that targets the treatment-refractory disease reservoirs, showing great preclinical efficacy against GBM recurrence. This potential therapeutic could also be trialed in patients with brain metastases that also express high levels of CD133. 

MANAGEMENT TEAM


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Dr. Sheila Singh 

Chief Executive Officer
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Dr. Jason Moffat

Chief Scientific Officer
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Dr. Parvez Vora

Director, Preclinical Development

CAREERS

NEWS

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Road Map

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Visit or call us today for a quotation or for any inquiries.

100 Biscayne Blvd. (North), 21st Floor, New World Tower, Miami, Florida 33148

(305) 555-4446