Dr. Sheila Singh


Dr. Sheila Singh, a co-founder of Empirica Therapeutics, is a world renowned brain tumour researcher and the chief pediatric neurosurgeon at McMaster Stem Cell and Cancer Research Institute.

Dr. Singh has extensive clinical and research experience in glioblastoma (GBM) and published the first description of isolating cancer stem cells from human brain tumours using CD133. Her lab has developed infrastructure and expertise in stem cell and GBM biology, target discovery, cancer cell signalling, pre-clinical models and drug testing to address the clinical challenge of GBM recurrence. The Singh lab’s access to patient samples has fostered the development of an innovative therapy-adapted patient-derived xenograft glioblastoma model.