Research Scientist I

Position: Research Scientist I (2 positions)

Term: 1-year contract to be converted to full time

Location: Hamilton, Ontario

Start date: June 2019 – May 2020 (flexible)

Deadline: Applications will be reviewed and only selected applicants will be contacted for an interview.

How to apply: Send your CV and a cover letter to

About Empirica Therapeutics

Empirica Therapeutics is developing a pipeline of innovative and transformative immunotherapies for cancers of high unmet need. Founded by Dr. Sheila Singh, a world-renowned neurosurgeon-scientist, and Dr. Jason Moffat, an international expert in functional genomics and gene-editing platforms, the company’s expertise and competitive advantage lies in its unique ability to develop candidates against the most aggressive and treatment-resistant forms of cancers, including glioblastoma (GBM) and brain metastasis (BM). 

We are a fast-paced, dynamic and patient-focused company that will inspire you and support your career. We are looking for employees who are passionate, adaptable, creative and have a capacity for constant innovation in pursuit of company goals. 

Responsibilities and Duties:

  • Design and develop strategies for novel T cell therapies
  • Plan and execute in vitro functional assays with human T cells
  • Create novel constructs for evaluating cellular therapy products for hard to treat solid cancer indications 
  • Maintain accurate records of research, and deliver scientific presentations and reports for internal meetings
  • Manage external resources (CRO and academic collaborations)
  • Integrate new ideas to support the company pipeline
  • Willing to wear many hats as is expected in a startup environment


  • Ph.D. in the field of Immunology, molecular biology, or related field with 0 – 3 years of experience in immuno-oncology 


  • Experience in T cell engineering, such as CAR-T or transgenic TCR T cells
  • Expertise in the characterization, culture, expansion and manipulation of T cells
  • Functional assays to measure cytokine release, proliferation and killing
  • Genetic manipulation using CRISPRs, TALENs, or ZFNs in mammalian cells
  •  Lentiviral vector design and cloning
  • Excellent oral and written communication skills
  • Strong problem-solving and analytical skills

Salary: Commensurate with experience

Principals only. Recruiters, please do not contact us.